Prime Tampa Heights location positioned within one of Tampa's fastest-growing and most active urban areas! Located in the rapidly growing Tampa Heights neighborhood, 105 W Columbus Drive presents a unique opportunity to own a distinctive multi-level property just minutes from Downtown Tampa. Renovated in 2015, the home blends historic character with modern updates. The over 3,000 square foot layout, combined with flexible zoning, supports a variety of living arrangements, including live-work use, operating a business, or income-producing opportunities. The property offers a flexible multi-level layout featuring 5 rooms, including 3 with ensuite bathrooms, along with an additional 1.5 bathrooms. The first level features an open layout with high ceilings and abundant natural light, creating an inviting space suitable for a reception area, living space, or workspace. This level includes two rooms and 1.5 bathrooms, along with a sizable kitchen with stainless steel appliances and granite countertops. A separate laundry and flex space located at the rear of the home provides additional functionality, ideal for storage, or utility use. The second level includes two private suites with ensuite bathrooms, highlighted by a spacious primary suite featuring a luxury bathroom with dual vanities, a walk-in closet, and a separate shower and tub. This level also features an expansive balcony overlooking the Downtown Tampa skyline, as well as a second covered balcony offering a more private outdoor setting. The third level features a private suite with a full ensuite bathroom, ideal for a dedicated office, guest space, or additional private quarters. The property includes ample parking with a paved driveway along the west side and additional parking along the east side accessible via a side alley. Situated in a prime Tampa Heights location, the property is just minutes from Armature Works, offering a wide variety of dining and entertainment options, as well as the Tampa Riverwalk. Nearby destinations such as Sprouts Farmers Market, Shuffle, Noble Rice, and Grand Cathedral Cigars further enhance the lifestyle appeal. With convenient access to major highways, the Gulf beaches, and just a short drive to University of Tampa, Water Street Tampa, and Sparkman Wharf, the property is centrally positioned within Tampa's urban core near downtown, major business districts, and key destinations. The property is also surrounded by significant redevelopment and investment, with nearby large-scale projects such as Gas Worx and continued development toward Ybor City enhancing the area's long-term growth. Additionally, the property directly to the south has proposed plans for a mixed-use development featuring ground-floor retail storefronts with over 250 residential units above, adding significant density and further reinforcing the continued growth of the neighborhood. Located within a designated Opportunity Zone, the property offers potential tax advantages for qualifying buyers. With its blend of historic charm, modern updates, flexible layout, and prime location in one of Tampa's most dynamic neighborhoods, 105 W Columbus Drive presents a truly unique opportunity. Opportunities like this are rare in Tampa Heights, call today to schedule your private showing and secure your position in one of Tampa's most dynamic growth corridors.